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The Novel Human Genetics Research Unit (NHG RU) was recently formed to identify and advance novel targets with a genetic association to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The NHG RU is therapeutically broad and complements other research units with strategic focus in immunology and oncology. The current portfolio includes assets entering FTIH studies, several programs in either LO or preclinical studies, and a broader effort in target validation, which includes novel targets emerging from the GSK-23andMe collaboration. The remit of the NHG RU is to identify novel targets, develop assets for clinical studies, and perform Phase 1 first time in human and proof of mechanism studies. When successful, assets will progress to Phase 2 and beyond within the GSK Development organization.
We have positions for laboratory-based scientists to conduct integrative pharmacology experiments that drive the discovery of medicines. The scientists will support preclinical efforts for target validation/lead optimization and may also support clinical programs. The grade level and accountabilities will be determined based on the applicant s fit to the specific needs of the research programs and years of experience. Below are details about the available positions:
Job Purpose and Key Responsibilities:
We are looking for professionals with these required skills to achieve our goals:
If you have the following characteristics, it would be a plus:
Our values and expectations are at the heart of everything we do and form an important part of our culture.
These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
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